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14.4. Insights into human genetic variation and population history from 929 diverse genomes

A Bergstrom , SA McCarthy , R Hui , MA Almarri , Q Ayub , P Danecek , Y Chen , S Felkel , P Hallast , J Kamm , H Blanche , JF Deleuze , H Cann , S Mallick , D Reich , MS Sandhu , P Skoglund , A Scally , Y Xue , R Durbin , C Tyler-Smith

To read the full abstract: Science 2020; 367(6484):eaay5012.These authors sequenced 929 whole-genome sequences from 54 geographically, linguistically, and culturally diverse human populations, as part of the Human Genome Diversity Project, a panel of global populations. The data represent African, Oceanian, and American-Indian populations. They identified 67.3 million single-nucleotide polymorphisms (SNPs), 8.8 million small insertions or deleti...

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ey0016.14-9 | (1) | ESPEYB16

14.9. Did our species evolve in subdivided populations across Africa, and Why does it matter?

Scerri Eleanor M.L. , Thomas Mark G. , Manica Andrea , Gunz Philipp , Stock Jay T. , Stringer Chris , Grove Matt , Groucutt Huw S. , Timmermann Axel , Rightmire G. Philip , d'Errico Francesco , Tryon Christian A. , Drake Nick A. , Brooks Alison S. , Dennell Robin W. , Durbin Richard , Henn Brenna M. , Lee-Thorp Julia , deMenocal Peter , Petraglia Michael D. , Thompson Jessica C. , Scally Aylwyn , Chikhi Lounes

To read the full abstract: Trends in Ecology & Evolution, 2018. 33 (8); 582594.This opinion piece argues that Homo sapiens evolved within interlinked groups living across Africa, and not in a single region of East Africa. Millennia of separation gave rise to diversity of human forms, and a complex mix of archaic and modern features in different places and...

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ESPE Yearbook of Paediatric Endocrinology

14.4. Insights into human genetic variation and population history from 929 diverse genomes

14.9. Did our species evolve in subdivided populations across Africa, and Why does it matter?

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